Tag: Biotech Stocks under $1

  • What is a Biotech Stock? Best Biotech Stocks to Invest in for the Long-Term

    What is a Biotech Stock? Best Biotech Stocks to Invest in for the Long-Term

    The biotech industry is poised for a resurgence, as scientists declare it to be the “golden age” of biotechnology.

    Remarkable scientific breakthroughs are opening unprecedented avenues for disease treatment and prevention.

    This presents a lucrative opportunity to enhance your investment portfolio by including valuable biotech stocks. But here the question arises what is a biotech stock?

    Fortunately, you don’t have to undertake extensive research or face the daunting task of identifying the best options.

    We have compiled a list of the top biotech stocks that hold the most promise for current investments. Seize the moment and make wise choices in this thriving sector.

    What Are Biotech Stocks?

    Biotech stocks are shares of companies operating in the biotechnology industry.

    Biotechnology is a field that applies biological and scientific principles to develop products and technologies for various industries.

    Those include healthcare, agriculture, and environmental preservation.

    Biotech companies often focus on areas such as pharmaceuticals, genetic engineering, medical devices, diagnostics, and bioinformatics.

    Knowing what is a biotech stock and investing in them allows individuals to participate in the growth and advancements of these companies.

    This will potentially benefit investors from their innovations and success.

    What Are Biotech Stocks

    What’s The Difference Between Biotech And Pharmaceuticals?

    While biotech and pharmaceuticals both operate within the healthcare industry, there are key differences between them.

    Pharmaceuticals typically refer to companies that develop and manufacture drugs using chemical synthesis.

    They often focus on small molecules and compounds synthesized in laboratories.

    In contrast, biotech companies utilize living organisms, such as cells or bacteria, to produce therapeutic proteins or develop treatments based on genetic engineering and manipulation.

    Biotech companies may also leverage cutting-edge technologies like gene therapy, RNA interference, or stem cell research.

    In essence, biotech companies harness the power of biology to create innovative therapies and solutions.

    Biotech Companies

    Biotech is a compelling investment opportunity, combining scientific advancements with economic potential.

    So here we have picked some of the best biotech stocks to be considered in 2023.

    1. Amgen Inc. (AMGN)

      In our quest of what is a biotech stock, the very first stock we have picked is Amgen Inc. (AMGN), a prominent American biopharmaceutical company.

      The company stands at the forefront of biologics and holds a significant position in global biotech markets.

      Their success can be attributed, in part, to their adeptness in mergers and acquisitions.

      In 2019, a partnership with Celgene resulted in the inclusion of Otezla in Amgen’s drug portfolio, while a 20.5% stake in BeiGene facilitated entry into the Chinese oncology market.

      The acquisition of Immunex Corporation granted access to the blockbuster drug Enbrel, and the recent purchase of Five Prime Therapeutics introduced the promising drug bemarituzumab.

      This strategic approach safeguards Amgen’s future growth despite forthcoming patent expirations.

      Amgen has formed a multi-year partnership with TScan Therapeutics to utilize TScan’s unique target discovery platform, TargetScan.

      The collaboration aims to identify the antigens that T cells recognize in Crohn’s disease patients.

      TScan will receive an upfront payment of $30 million and stands to earn more than $500 million through preclinical, clinical, regulatory, and commercial milestones, along with royalty payments.

      Amgen will explore various modalities for developing therapeutics based on the identified targets and will hold exclusive global rights for development and commercialization.

      Additionally, Amgen has the option to extend the collaboration to include ulcerative colitis, subject to specific conditions.

      Amgen stands out on our list due to its robust financial profile and its performance in the recently reported quarter.

      Despite a minor 2% decline in sales at $6.1 billion, its earnings soared by an impressive 97% to $5.28 per share.

      Moreover, the company offers an attractive dividend yield of 3.83%.

      With a combination of these strengths and a stable price over the last three months, Amgen emerges as an excellent biotech stock to consider adding to your portfolio.

    2. Biogen Inc. (BIIB)

      Biogen Inc. (BIIB), a prominent biotech company based in the United States, takes its place on our list of noteworthy biotech stocks.

      Despite the controversies surrounding its drug Aduhelm and the intensifying competition from generic alternatives, Biogen cannot be overlooked.

      In a recent development, Biogen, in collaboration with Eisai Co., Ltd., announced a significant achievement.

      The Peripheral and Central Nervous System Drugs Advisory Committee (PCNS) of the U.S. Food and Drug Administration (FDA) unanimously validated the efficacy of LEQEMBI.

      The drug is also known as lecanemab and is used in treating Alzheimer’s disease (AD).

      The committee’s evaluation was based on the conclusive data from Eisai’s Phase 3 Clarity AD clinical trial.

      LEQEMBI, a result of the strategic research alliance between Eisai and BioArctic, demonstrated a favorable overall benefit-risk profile, as affirmed by the committee members.

      Notably, the drug’s marketing authorization application has been submitted to the Ministry of Food and Drug Safety (MFDS) in South Korea.

      This marks the first application for lecanemab in Asia outside of Japan and China. Eisai intends to file additional applications in various Asian countries.

      Furthermore, Health Canada has accepted a New Drug Submission (NDS) for LEQEMBI, acknowledging its potential and significance in the healthcare landscape.What is a Biotech Stock

      Despite the expiration of the Tecfidera patent and increased generic competition, Biogen remains financially strong.

      Last quarter, the company’s earnings surged 30% to $387.9 million ($2.67 per share).

      Although the cash balance decreased by 18% to $2.9 billion, sales reached $2.46 billion, surpassing expectations despite a slight decline.

      With a share price up by almost 56% since last year, Biogen is an attractive stock to consider adding to your portfolio and holding onto.

    3. Bio-Techne Corporation (TECH)

      As part of our journey to discover what is a biotech stock, we are adding Bio-Techne (TECH) to our stock lineup.

      This U.S.-based biotech company specializes in supplying life science reagents, instruments, and services to global research, diagnostics, and Bioprocessing markets.

      Unlike other biotech firms on our list, Bio-Techne offers investors a gateway into the thriving genomics industry, predicted to grow at an impressive 16.87% by 2030 to $98.7 billion.

      With a rich legacy of innovation, Bio-Techne has amassed an extensive array of proteomic research reagents, empowering groundbreaking scientific breakthroughs.

      This exceptional feature further enhances the appeal of investing in this biotech gem. In spite of its already substantial presence, Bio-Techne continues to forge ahead with its expansion efforts.

      One recent endeavor involved the augmentation of their Advanced Cell Diagnostics (ACD)-branded RNAscope in situ hybridization (ISH) portfolio.

      That was through the introduction of an RNAscope multiomic workflow compatible with the Standard BioTools Hyperion Imaging System.

      The integration of multiomic spatial imaging into the Hyperion Imaging System presents an unprecedented opportunity to generate intricate and comprehensive tissue architectural maps.

      It establishes connections between transcripts, proteins, and signaling networks within tissues.

      The technology enables the assessment of drug efficacy, the discovery of innovative intervention methods, and the identification of informative biomarkers.

      Consequently, it possesses the potential to become a cornerstone of precision medicine approaches in the future.

      Moreover, Bio-Techne boasts an appealing financial profile, including a dividend payout of 0.43%.

      During their most recent fiscal quarter, which concluded on March 31, 2023, the company achieved organic revenue of $294.1 million, marking a respectable 3% year-over-year growth.

      Additionally, quarterly earnings per share rose from $0.37 in the previous year to $0.43.

      Considering the substantial potential for growth, the reduced risk factor, and the company’s robust financial standing, investing in Bio-Techne stock is a highly favorable decision.

      Furthermore, the current market volatility has caused the stock to trade at a price that remains approximately 9.5% lower year-to-date, presenting an advantageous buying opportunity.

    4. Exelixis Inc (EXEL)

      Exelixis Inc (EXEL), a U.S.-based biotech company focused on oncology, stands out as a resilient player in the market.

      Nonetheless, Exelixis remains committed to its core objectives and has made substantial strides in advancing its commercial endeavors and expanding its pipeline.

      CABOMETYX is a leading tyrosine kinase inhibitor for renal cell carcinoma.

      It maintained its position in the first quarter, primarily attributed to its successful utilization in combination with nivolumab for first-line treatment.

      The company has also made notable progress across various pipeline programs, including the STELLAR-303 and STELLAR-304 Phase 3 trials for zanzalintinib.

      EXEL also progressed well as the phase 1 trial of XB002, exploring single-agent and combination dose-escalation cohorts.

      Exelixis aims to initiate pivotal studies for zanzalintinib in 2023 and expedite the full development of XB002 by year-end.

      Notably, the company has also achieved steady advancements through collaborations with Cybrexa and Sairopa.

      Sairopa received FDA clearance for its Investigational New Drug application for ADU-1805 in February, followed by the commencement of a phase 1 study in March.

      In terms of financials, Exelixis witnessed a 15% year-over-year revenue growth in Q1 2023, totaling $408.79 million.What is a Biotech Stock - Growth

      However, increased research and development (R&D) as well as selling, general, and administrative (SG&A) expenses led to a 40% decline in income, settling at $40 million.

      Looking ahead, the company anticipates full-year revenue ranging from $1.78 billion to $1.88 billion in 2023.

      Consequently, with a modest 7% price performance over the past 12 months, Exelixis presents an attractive opportunity for investors.

      It will not only diversify their portfolios but also offers a promising biotech stock poised for growth.

    5. Corcept Therapeutics Incorporated (CORT)

      Corcept Therapeutics (CORT) emerges as a prominent player in the biotech sector.

      It specializes in the development of drugs that effectively manage unstable cortisol levels and associated disorders.

      At the forefront of their product lineup is Korlym, a groundbreaking treatment approved for Cushing’s syndrome in type 2 diabetes patients.

      This drug holds orphan status and exclusive rights until 2037 for Cushing’s, and Corcept is diligently working towards securing approvals for additional indications.

      The potential for Korlym’s expansive market reach is immense, given its multiple applications.

      To further enhance physicians’ ability to identify and treat patients with hypercortisolism, CORT is making substantial investments.

      A noteworthy initiative is the recently established CATALYST study, which holds promise for significant growth in the field of Cushing’s syndrome treatment.

      From a financial standpoint, Corcept Therapeutics demonstrates exceptional performance.

      In the first quarter of 2023 alone, the company experienced a remarkable 13% revenue increase, amounting to $105.66 million.

      Moreover, Corcept boasts a net income of 15 cents per share, while maintaining a robust cash balance of $465.06 million by the end of the quarter.

      Notably, the company’s return on equity stands well above the industry average, at an impressive 19.40%.

      Considering the impressive progress in Corcept’s pipeline and its recent one-month price decline of 5%, an opportune moment arises for potential investors.

      With its proven track record, strong financial profile, and promising growth prospects, Corcept presents a compelling buying opportunity.

      CORT may also yield significant returns as the company’s stock price is poised to soar once again.

    To further explore what is a biotech stock and which are performing well, we have carefully selected 20 tickers here that represent the top 20 biotech stocks with outstanding performance, exceeding 80% YTD.

    These promising options are poised to make a significant impact in 2023, offering the potential for substantial returns.

    20 Best Performing Biotech Stocks

    No. Ticker Company Market Cap (in million) Performance (YTD) Price
    1 AMAM Ambrx Biopharma Inc. 788.28 556.22% 14.9
    2 GNLX Genelux Corporation 856.95 457.80% 34.31
    3 BMEA Biomea Fusion, Inc. 1407.4 336.89% 36.83
    4 IMGN ImmunoGen, Inc. 4163.14 273.08% 18.5
    5 PTGX Protagonist Therapeutics, Inc. 1659.44 161.96% 28.58
    6 MLTX MoonLake Immunotherapeutics 1410.18 161.19% 27.42
    7 IRON Disc Medicine Opco Inc 837.9 146.35% 49
    8 RETA Reata Pharmaceuticals, Inc. 3850.63 140.91% 91.52
    9 NVCT Nuvectis Pharma, Inc. 286.81 140.27% 18.02
    10 VKTX Viking Therapeutics, Inc. 2283.33 139.36% 22.5
    11 CBUS Cibus, Inc. 56.84 137.15% 17.49
    12 TGTX TG Therapeutics, Inc. 4285.47 126.29% 26.77
    13 MORF Morphic Holding, Inc. 2706.85 123.08% 59.67
    14 TYRA Tyra Biosciences, Inc. 642.07 116.91% 16.49
    15 VYGR Voyager Therapeutics, Inc. 555.08 111.23% 12.89
    16 BBIO BridgeBio Pharma, Inc. 2759.99 105.77% 15.68
    17 VECT VectivBio Holding AG 1047.68 93.25% 16.75
    18 HEPA Hepion Pharmaceuticals, Inc. 49.52 92.47% 11.56
    19 ELTX Elicio Therapeutics, Inc. 84.96 82.63% 14.82
    20 RXDX Prometheus Biosciences, Inc. 9549.57 81.77% 199.95

    We have also compiled a list of the 5 best biotech penny stocks which has performed well this year. These penny stocks could be a better investment opportunity for long term growth.

    These stocks are currently trading at relatively low prices and have the potential to generate good returns over time.

    Best Biotech Penny Stocks

    No. Ticker Company Market Cap (in million) Performance (YTD) Price
    1 VYNE VYNE Therapeutics Inc. 18.67 73.33% 4.68
    2 DBTX Decibel Therapeutics, Inc. 112.82 114.63% 4.4
    3 LSTA Lisata Therapeutics, Inc. 35.06 70.75% 4.32
    4 ASLN ASLAN Pharmaceuticals Limited 64.28 116.13% 3.89
    5 NAUT Nautilus Biotechnology, Inc. 426.56 112.78% 3.83

    Taking the exploration of what is a biotech stock a step further; we have compiled a list of some of the best biotech stocks under $1.

    These biotech stocks under $1 could prove to be a good investment for long term growth.

    The biotech stocks under $1 are currently trading at a relatively low price and may be able to generate good returns in the future.

    Best Biotech Stocks Under $1

    No. Ticker Company Market Cap (in million) Performance (YTD) Price
    1 EFTR eFFECTOR Therapeutics, Inc. 52.16 131.52% 0.99
    2 ERYP ERYTECH Pharma S.A. 32.19 142.35% 0.8
    3 PHGE BiomX Inc. 15.38 88.06% 0.35
    4 VBLT Vascular Biogenics Ltd. 18.99 102.58% 0.24
    5 ATOS Atossa Therapeutics, Inc. 113.96 67.70% 0.89

    What Drives Biotech Stocks?

    Several factors can drive the performance and volatility of biotech stocks:

    Examples Of Price Swings

    Biotech stocks are particularly sensitive to events such as clinical trial results, regulatory approvals, and market sentiment.

    Positive clinical trial data or regulatory milestones, such as receiving approval from the U.S. Food and Drug Administration (FDA), can significantly impact stock prices.

    Conversely, negative trial results or regulatory setbacks can lead to sharp declines.

    Additionally, broader market trends, investor sentiment toward the biotech sector, and the overall economic climate can also influence biotech stock prices.

    How To Invest In Biotechnology

    Investing in biotechnology can be done through various avenues:

    • How To Invest in Biotechnology Stocks?

      If you want to know how to invest in biotech stocks, it is better to purchase individual stocks of biotech companies.

      Before investing, it is crucial to research and analyze the financial health, product pipeline, and competitive position of the companies in consideration.

      Understanding the risks associated with the specific biotech sector and diversifying investments across multiple companies can help manage risk.

    • How To Invest in Biotechnology ETFs?

      Biotechnology-focused Exchange-Traded Funds (ETFs) offer a convenient and cost-effective way to gain exposure to the biotech sector.

      Investors in search of how to invest in biotech stocks can also use ETFs as an alternative and more promising option. ETFs offer a diversified approach to investing in the targeted sector.

      Biotech ETFs consist of a basket of biotech stocks, providing exposure to multiple companies within the industry.

      This approach can help reduce risk by spreading investments across different companies and potentially capturing broader industry trends.

    What’s The Outlook for Biotechnology?

    The outlook for biotechnology is generally positive due to ongoing advancements in healthcare, increasing demand for innovative treatments, and the potential for transformative discoveries.

    According to Data Bridge Market Research analyses, the global biotechnology market is expected to reach $10 trillion by 2030, at a compound annual growth rate (CAGR) of 29%.

    However, the industry can also face challenges related to clinical trials, regulatory hurdles, and competition.

    It is important to stay informed about the latest developments, regulatory changes, and market trends when considering investments in biotech.

    Risks Of Biotechnology Stocks

    Investing in biotech stocks involves certain risks that investors should be aware of:

    • Clinical Failure

      Biotech companies often conduct clinical trials to evaluate the safety and efficacy of their products.

      However, there is always a risk of clinical failure, where a drug or treatment does not meet the desired endpoints.

      Negative trial results can lead to significant stock price declines, as it may delay or halt the product’s development and commercialization.

    • Regulatory Issues

      Regulatory approval is a critical milestone for biotech companies. The FDA and other regulatory bodies have stringent requirements for safety and efficacy.Regulatory Issues

      Delays or rejections in obtaining approvals can negatively impact stock prices.

      Additionally, changes in regulations or unexpected adverse events related to approved products can also affect the performance of biotech stocks.

    Developing The Market

    Biotech companies face specific challenges in developing and commercializing their products including:

    • Patent Expiration

      Patents play a vital role in protecting the intellectual property of biotech companies.

      However, patents have limited lifespans, and once they expire, other companies can produce generic versions of the drug, potentially leading to a decline in sales and market share.

      Companies must continuously innovate and develop new products to stay competitive after patent expiration.

    Challenges With Researching Biotech Stocks

    Researching biotech stocks can be complex and challenging due to several factors:

    • Scientific Complexity

      Understanding the scientific concepts and technical aspects of biotech companies requires specialized knowledge and expertise.

    • Pipeline Evaluation

      Assessing the potential of a company’s product pipeline, clinical trial outcomes, and market prospects demands careful analysis and understanding of the regulatory landscape.

    • Volatility

      Biotech stocks can be highly volatile, making it challenging to predict future performance accurately.

    Best Online Brokers for Biotech Penny Stocks

    Investing in biotech penny stocks, which are low-priced stocks, typically involves higher risk and volatility.

    To better understand how to invest in biotech stocks online, it is important to choose reputable and reliable online brokers.

    Suitable brokers offer access to these stocks while providing robust trading platforms, research tools, and competitive pricing.

    Some popular online brokers known for their biotech offerings include Charles Schwab, TD Ameritrade, Fidelity, E*TRADE, and Interactive Brokers.

    However, it is advisable to conduct thorough research and consider individual preferences before selecting a specific broker.

    Conclusion

    In conclusion, biotech stocks offer investors an opportunity to participate in the advancements of the biotechnology industry.

    However, it is important to under what is a biotech stock and carefully evaluate the risks. Investors should also conduct thorough research, and stay informed about the latest developments in the sector before making investment decisions.

    Diversification, understanding the scientific and regulatory landscape, and staying abreast of market trends are crucial elements in navigating the biotech investment landscape.

    Frequently Asked Questions

    Which Biotech Penny Stocks Should I Buy?

    As an AI language model, I cannot provide real-time financial advice or stock recommendations.

    It is important to conduct thorough research and consult with a financial advisor before making any investment decisions.

    Biotech penny stocks can be highly volatile and risky, so it’s crucial to evaluate the company’s financials, pipeline, and market potential before investing.

    Is Biotech a Safe Investment?

    Biotech, a rapidly evolving field, presents opportunities and risks as an investment.

    While breakthroughs in healthcare, agriculture, and energy hold immense potential, regulatory challenges, clinical trial outcomes, and patent disputes introduce volatility.

    Thorough research, diversification, and understanding of industry dynamics are essential to navigate this complex landscape and make informed investment decisions.

  • What Are Biotech Stocks And How To Invest In Them

    What Are Biotech Stocks And How To Invest In Them

    In this article, we are going to help you understand everything there is about biotech companies ranging from what they are- all the way to- how to invest in biotech stocks. This will help you hit the nail on the head with the trend analysis and strategically make investments in this type of stock.

    Biotech stocks have been in the public’s portfolio right since the inception of the stock market and exchange platforms. But just like the recent surge in Green Energy stocks, EV stocks, and Crypto stocks, we are seeing a new rise and shift in the Biotech stocks’ popularity.

    This both excites the investors as well as creates curiosity over what actually is prompting the rise in biotech company stocks and biotech stock prices. This curiosity is essential for looking into the reasons why the Biotech stocks are trending and analyzing the patterns which are making this type of stock boom. This gives investors and stock analysts an edge in predicting and identifying signals and hints in the market shifts due to internal and external reasons.

    What are biotech stocks?

    Biotech Stocks are essentially publicly traded companies that focus on the development, production, and commercialization of pharmaceutical products and services that are used in the treatment of diseases. The therapeutics and treatments that you consume or apply in daily life, acquiring from pharmacies or hospital dispensaries exist because a Biotech company developed them.

    From a stock perspective, the biotech stock value ranges from triple-digit share prices all the way to under $1 price per share. The ones that are under $5 share prices are known as biotech penny stocks. These, just like every other penny stock are attributed to a lot of volatility however Biotech stocks have their own intrinsic share of volatility and risks (which come along with rewarding outcomes as well). Before we get into that let us first explain what really is creating the hype in this kind of stock, in the first place.

    How Biotech Industry became very popular among investors

    We mentioned before that the trend in the biotech stock is growing as it is in Green energy, Crypto, and EV stocks. But the reason behind this trend is completely different and associated to unique factors.

    Covid-19 Pandemic

    One major reason for the rise is the COVID-19 pandemic, specifically the race for vaccine production. When the pandemic had gripped the world in its virus, it had paralyzed many markets and business; the overall global economy was halted. In fact, even the most successful biotech companies had been forced to shut down. But Pandemic being human health and medical crisis had prompted responses from the very biotech industry that it had halted. The Biotech industry decided to push for solutions to the Pandemic and the virus, in the form of Vaccines. The vaccines became a huge market space in the healthcare industry and biotech stocks immediately started filling it up.

    The aging population

    According to the Rural Health Information Hub, The US population has more than 46 million citizens above or at the age of 65 which is expected to grow to 90 million almost in 2050. Every one in five Americans will be aged over 65 years old. The context of this is important when you correlate the use of prescribed medicines and drugs with old age; the older population uses prescribed medicines and drugs more often to treat their chronic illnesses and complications, as compared to younger generations. This means demand and innovation required from the Biotech Companies will increment in the following years and push the companies to focus on targeting innovative and niche spaces in the pharmaceutical market as competition concentrate between biotech companies.

    Exposure to Biotech stock

    The former factor is a more prevalent cause of exposure in the biotech market in the current market trend than the latter because the US and the overall world economy is slowly coming out of the Pandemic and rolling out vaccines. The pandemic had crippled many portfolios for the investors in various stocks and companies. During this time, the biotech stock was prevailing due to public, government, and private investors nudging the biotech companies to create vaccinations. This made investment profiles in the Biotech stock especially the ones in the vaccination race, more attractive.

    What are the types of Biotech Stocks?

    Now that we have established the roots of the developing trend in the Biotech industry, let’s focus on what exactly are the cues to look for when you are investing in the Biotech companies stock.

    There are three main types of Biotechnology companies; Medical, Agriculture, and industrial ( or referred to as Red, Green, and White respectively).

    The primary thing to focus on when you invest in Biotech companies is to have a bird’s eye view of all the metric and indicator for the stages and process that are related to Biotech stock’s operations/performances. This helps ensure, that your investment decision is based on solid evidence that can hopefully turn out to be incredibly rewarding.

    Biotech operations and drug development, especially in the Medical type, goes through rigorous testing that are subject to stringent approvals and regulatory standards. These operations, based on the development and approval are broken down into 5 stages.

    Investment and the five stages of Biotech Stock operations

    The first stage of drug development is known as Research and Discovery, where concepts and theories of new products are formed along with a given conceptual framework to back up the attributes and potential of the new product.

    The second stage is known as Preclinical Stage, where the drug’s pharmacological profile is created to assess the strategies and planning of human testing and effects that are expected to result from the early and late clinical stages. This profile is assessed by the regulatory bodies like the US FDA, to be approved and taken to the next stage human trials and tests. These trials and tests take place in 4 phases;

    • Phase 1: The safety of the drug is evaluated in human trials with determination to predict dosage range.
    • Phase 2: The efficacy of the drug is tested relevant to the disease it is targeting. This phase is known as proof of concept (PoC).
    • Phase 3: The proof of concept and previous phases are tested again in large population batches with several thousand people. This phase is known as regulatory proof which when approved requires the next step of New Drug Application (NDA) approval in order for the drug to be marketed.
    • Phase 4: Once the drug is marketed, the companies voluntarily or as per the requirement of the FDA will undertake post approval studies to validate and add additional information about the drug’s safety and efficacy.

    The third stage is known as Early-clinical stage in which the companies start initiating the phases of the testing and study. The first two phases mentioned above are what comes into this stage of Biotech companies. These companies that are in the first two phases are known as Early-stage biotech companies.

    The fourth stage is known as the late-clinical stage and the company is known as late-stage biotech. This stage consists of the regulatory approvals and NDA signing of the drug from the FDA.

    The fifth and final stage is the Commercial Stage, in which the companies have been approved for the NDA and begin rolling out the commercial strategies for the market. This stage also includes Phase 4 study as per requirement or voluntary basis.

    How to Invest in Biotech Stocks

    It may click to you up till this point that the biotechnology companies out there are in different stages of the Biotech lifecycle and thus have different risks associated with each stage for investment. The more progressed and approved the company is, in its stages, the more profitable and attractive its stock looks- however it still remains risky. Biotech Industry Organization (BIO) researched that the likelihood of success and regulatory approval to be received for a company from Phase I to Commercial stage has been 9.6% from data stretching 2006-2015. However, in the 2011-2020 data study, it was reduced to 7.9% which is mainly attributed to the concentration and new entrants in the market.

    The report also showed that even the hottest areas of a biotech investment portfolio which are Neurology, Cardiovascular, and Oncology have an approval rate of 8.4%, 6.6%, and 5.5% respectively. This report was also discussed by the Motley Fools team on their Youtube Channel in which they broke down the approval and success rating according to phases 1 to 4 (Commercialization), which was 70%, 33%, 30%, and less than 10% respectively.

    Failure is the big bad wolf in the biotech stock investment

    The investors need to lookout for the stage that the companies are in, in order to assess if the Biotechnology Company is worth investing into. Furthermore, it is important to heed for investors that companies can fail at any one of these stages which is what makes Biotech stocks volatile and risky. However, while looking into the track record of previous drug approvals of the company as well as the financials of the company, you can make a strong investment. The opposite is also true, once the company has been approved for any one of these stages and progresses, the stock price shoots up to double and triple digit percentages, while in some cases it can shoot up to quadruple digit percentages!

    Other proven ways to invest in Biotech Stock

    Looking at one biotech company’s stock for investment may seem to be tricky sometime, if there aren’t enough indicators to decide if the stock is valuable or not. In cases like these, especially if you are a new investor looking for exposure into the Biotech Industry, the safest bet is to opt for Exchange Traded Funds (ETFs) for biotechnology stocks. Biotech ETFs provide a great space for a new investor to get an exposure into Biotech stocks. Depending on your curiosity and preference you may opt for an equal-holding weight ETF or a market weighted ETF. The former will give you equal exposure to small new biotech stocks as you would get from big blue chip Biotech stocks.

    Another great strategy that has been evolving in the Biotech stock investment is the focus on Contract Research Organizations. Many Biotech stocks discover an idea for their drug candidate and then proceed to outsource the administrative, regulatory, experimentation, and clinical procedures to a CRO which is well equipped for exactly this sort of specialization in the Biotech space. These CROs generate revenue for their services despite the approval or disapproval of the product in any of the stages. Furthermore, big-fish CROs focus on the M&A action where they realize the potential of a new product candidate for which it merges, acquires or partners with the product’s Biotech company and reaps the gains from owning the candidate through its development and approvals. Therefore, investing in Biotech CROs may prove to be a better investment than just the developing Biotech Companies.

    Biotech Penny Stocks under $1

    A great way to start exposing yourself to Biotech stocks is to find biotech penny stocks which are $1 or under. Usually, investors invest in multiple under $1 portfolios to broaden their exposure. Here is a list of Biotech Penny stocks under $1.

    Ticker Company Market Cap Performance (YTD) Price Change
    AEZS Aeterna Zentaris Inc. 109.74 106.82% 0.88 2.11%
    ACST Acasti Pharma Inc. 116.17 71.54% 0.56 -1.24%
    ADXS Advaxis, Inc. 85.82 66.91% 0.58 23.31%
    ZSAN Zosano Pharma Corporation 95.38 64.01% 0.86 -3.94%
    OGEN Oragenics, Inc. 78.24 48.33% 0.67 -1.33%

    Biotech Stocks under $5

    Similarly, if you want to upgrade your investment portfolio from $1 biotech stocks, investors opt for bigger share price and market cap range for their portfolio and as such, focus on $5 or under Biotech stocks to invest in. This adds slightly more reward and risk but still provides great exposure.

    Ticker Company Market Cap Performance (YTD) Price Change
    SESN Sesen Bio, Inc. 755.67 203.70% 4.10 -3.53%
    PTIX Protagenic Therapeutics, Inc. 38.77 152.38% 2.65 -1.85%
    CTXR Citius Pharmaceuticals, Inc. 353.83 111.76% 2.16 0.47%
    MRKR Marker Therapeutics, Inc. 234.82 89.66% 2.75 -1.79%
    OTLK Outlook Therapeutics, Inc. 441.29 86.15% 2.42 1.68%