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Tag: Kazia stock

  • Kazia Therapeutics (KZIA) Rides High On New Research Findings

    Kazia Therapeutics (KZIA) Rides High On New Research Findings

    The stock value of Kazia Therapeutics Limited (NASDAQ: KZIA) had a significant increase in the most recent trading session, rising 92.19% to $10.10. This notable increase came after promising preclinical findings were published in the prestigious journal Molecular Cancer Therapeutics, which is affiliated with the American Association for Cancer Research.

    Paxalisib Could Revolutionize TNBC’s Business

    The recently released research focuses on the potential of paxalisib, Kazia’s primary experimental medicine, to transform the management of triple-negative breast cancer (TNBC), a highly aggressive and resistant cancer subtype.

    The study, which is headed by Professor Sudha Rao of the QIMR Berghofer Medical Research Institute, demonstrates how paxalisib can improve immune responses and change the tumor microenvironment. The medication showed synergistic anti-cancer benefits when used in conjunction with immune checkpoint inhibitors, which is encouraging as these immunotherapies become more popular in oncology.

    Combined Therapeutic Potential and Mechanistic Understanding

    One of the study’s main conclusions is that, in comparison to PI3K inhibition alone, combined inhibition of the PI3K and mTOR pathways is more effective at preventing tumor development and cell migration. Additionally, paxalisib was demonstrated to enhance CD4+ and CD8+ T cell infiltration and activation within TNBC tumors, highlighting its promise in immune-based cancer treatments.

    Paxalisib and pembrolizumab (KEYTRUDA) together decreased tumor burden and increased survival rates in preclinical animals, confirming the usefulness of this combination therapy approach.

    Advancements in Clinical Use

    These results have set the stage for Kazia’s newly launched Phase 1b clinical study, which will assess paxalisib in patients with advanced breast cancer in conjunction with checkpoint inhibitors and chemotherapy. An important step in converting preclinical promise into clinical benefit is this experiment.

    According to Kazia, this result enhances paxalisib’s therapeutic potential beyond brain malignancies and places it as a top contender for next-generation immunotherapy for solid tumors.

    “Combination of the PI3K/mTOR inhibitor paxalisib with immune checkpoint inhibitors enhances antitumor activity in preclinical models of triple-negative breast cancer,” states the study, which provides a strong basis for additional clinical investigation.

  • What changed for these 50 stocks in Pre-Market Session?

    What changed for these 50 stocks in Pre-Market Session?

    Oncternal Therapeutics Inc. (ONCT) stock soared 2.42% to $2.96 in the pre-market trading as the company raised the size of the formerly publicized offering and purchase on a firm commitment basis 7,258,065 shares of common stock of the Company, at a price to the public of $3.10 per share, less underwriting discounts, and commissions.

    JOYY Inc. (NASDAQ: YY) shares are trading up 19.13% at $87.75 at the time of writing as the Company revealed its Q3, 2020 Earnings. Analysts have a consensus price target of $125. The company’s 52-week range was noted as $41.33 to $108.21.

    Aptevo Therapeutics Inc. (APVO) grew over 38.17% at $48.9 in pre-market trading today after the firm offered an update on ALG.APV-527, a novel immunotherapeutic bispecific candidate aimed for the cure of multiple solid tumors expressing 5T4, a tumor-restricted antigen.

    Zomedica Pharmaceuticals Corp. (ZOM), a Drug Manufacturers – Specialty & Generic company, dropped about -2.19% at $0.1428 in pre-market trading Thursday as the firm announced its Q3 2020 results.

    Nxt-ID Inc. (NXTD) stock moved down -1.99 percent to $0.35 in the pre-market trading after the Corporation declared to adjourn the annual meeting of shareholders.

    MoneyGram International Inc. (MGI) lost over -7.9% at $6.7 in pre-market trading Thursday 19 November 2020, as the company posted 150% year-over-year cross-border deal and revenue growth for October in its direct-to-consumer digital business, MGO.

    Lexicon Pharmaceuticals Inc. (LXRX) is up more than 2.5% at $1.64 in pre-market hours Thursday 19 November 2020 following the company revealed to participate in Stifel 2020 Virtual Healthcare conference on Wednesday, November 18, 2020. The stock had dropped over -11.60% to $1.60 in the last trading session.

    Before the trading started on 19 November 2020, UP Fintech Holding Limited (TIGR) is up 4.61% to reach $5.9 after the Company announced to unveil its quarterly results on November 25, 2020. It has been trading in a 52-week range of $2.03 to $7.60.

    Asia Pacific Wire & Cable Corporation Limited (APWC) stock plunged -4.72% to $2.02 in the pre-market trading as the Corporation publicized that it will organize its 2020 Annual General Meeting on September 18, 2020, at 9:00 a.m. New York time at its headquarters located at Room B, 15th Floor, No. 77, Section 2, Dunhua South Road, Taipei, 106, Taiwan and (2) the Company has procured a US$6,000,000 secured loan from its majority shareholder, Pacific Electric Wire & Cable Co., Ltd.

    Marathon Patent Group Inc. (NASDAQ: MARA) shares are trading down -0.35% at $2.88 at the time of writing following Bitcoin self-mining company has disclosed a new investor presentation, which contains updated economic information as of November 5, 2020. The company’s 52-week range was noted as $0.35 to $5.25. Analysts have a consensus price target of $8.

    Futu Holdings Limited (FUTU) grew over 10.7% at $47.6 in pre-market trading today after the company publicized its 3rd quarter scores.

    L Brands Inc. (LB), and Apparel Retail company, rose about 16.04% at $39.0 in pre-market trading Thursday as the firm announced upbeat earnings results.

    Agora Inc. (API) stock moved up 2.45 percent to $35.99 in the pre-market trading after the Tech-giant announced its Q3 2020 results.

    ObsEva SA (OBSV) gained over 3.38% at $2.14 in pre-market trading Thursday 19 November 2020 as the biotech-firm declared the positive topline results of PROLONG, the Phase 2a proof-of-concept, randomized, double-blind, placebo-controlled trial of laropiprant in preterm labor.

    Bilibili Inc. (BILI) is up more than 4.49% at $50.0 in pre-market hours Thursday 19 November 2020, after the Corporation revealed its third-quarter 2020 results. The stock had dropped over -4.40% to $47.85 in the last trading session.

    Before the trading started on 19 November 2020, Youdao Inc. (DAO) is up 3.9% to reach $26.13, as it revealed quarterly results for the fiscal third quarter. It has been trading in a 52-week range of $13.20 to $47.70.

    Oragenics Inc. (OGEN) stock plunged -6.27% to $0.4377 in pre-market trading.

    SPI Energy Co. Ltd. (NASDAQ: SPI) shares are trading up 3.51% at $8.25 at the time of writing, as the Energy sector firm announced that its completely-owned SPI Solar, subsidiary completed the sale of a 1.015-megawatt solar project located on Hawaii’s Maui island. The company’s 52-week range was noted as $0.55 to $46.67.

    Gold Fields Limited (GFI) tumbled over -3.19% at $9.42 in pre-market trading today, following the Company revealed operational details for the 3-month period ending September 30, 2020.

    Marin Software Incorporated (MRIN), a Software – Application company, dropped about -3.38% at $2.0 in pre-market trading Thursday.

    X Financial (XYF) stock moved up 99.14 percent to $1.39 in the pre-market trading as the company disclosed that it will hold its 2020 annual general meeting of shareholders at its offices at 7/F, Block A, Aerospace Science and Technology Plaza, No.168 Haide Third Avenue, Nanshan District, Shenzhen, China on December 11, 2020, at 10:00 a.m., Beijing Time.

    Simon Property Group Inc. (SPG) lost over -2.43% at $74.75 in pre-market trading Thursday 19 November 2020 after the news that Simon has valued an upsized public offering of 19,250,000 shares of common stock at a public offering price of $72.50 per share that is expected to close November 23, 2020, subject to the satisfaction of customary closing conditions.

    ZoomInfo Technologies Inc. (ZI) is up more than 2.55% at $40.6 in pre-market hours Thursday 19 November 2020, as the Company revealed its Q3 2020 Earnings results. The stock had dropped over -2.85% to $39.59 in the last trading session.

    Before the trading started on 19 November 2020, Pan American Silver Corp. (PAAS) is down -2.98% to reach $29.98, after the Company Q3 results matched the predictions. It has been trading in a 52-week range of $10.61 to $40.11.

    Leap Therapeutics Inc. (LPTX) stock soared 6.67% to $1.6 in the pre-market trading, as the Company posted Q3 2020 Earnings results. The most recent rating by Piper Sandler, on June 29, 2020, is at an Overweight.

    Hudson Capital Inc. (NASDAQ: HUSN) shares are trading up 33.93% at $3.0 at the time of writing, following news of Hudson Capital Inc. and FreightHub, Inc. progressing further with the planned merger. The company’s 52-week range was noted as $1.60 to $9.80.

    Transocean Ltd. (RIG) grew over 4.07% at $1.28 in pre-market trading today, as the firm reported deep-water Corcovado, deep water Mykonos contract extensions.

    Acasti Pharma Inc. (ACST), a Biotechnology company, rose about 4.55% at $0.23 in pre-market trading Thursday, after the firm revealed Q2, 2021 fiscal results.

    Orbital Energy Group Inc. (OEG) stock moved up 3.56 percent to $0.8 in the pre-market trading, as the company posted Q3, 2020 earnings reports.

    Ideanomics Inc. (IDEX) gained over 10.34% at $1.28 in pre-market trading Thursday 19 November 2020 after the firm announced MEG October & Q4 sales activity.

    Virgin Galactic Holdings Inc. (SPCE) is up more than 2.04% at $23.05 in pre-market hours Thursday 19 November 2020 after the Analysts decreased its estimates by almost 25%. The stock had jumped over 5.81% to $22.59 in the last trading session.

    Before the trading started on 19 November 2020, Washington Prime Group Inc. (WPG) is down -2.15% to reach $0.742 after the report of the company to present at REITworld 2020 Virtual Investor Conference. It has been trading in a 52-week range of $0.49 to $4.49.

    Kintara Therapeutics Inc. (KTRA) stock soared 1.79% to $1.71 in the pre-market trading, after the company announced Q1, 2021 results and offered a business update.

    Electra Meccanica Vehicles Corp. (NASDAQ: SOLO) shares are trading up 7.53% at $7.43 at the time of writing. The company’s 52-week range was noted as $0.89 to $7.91.

    K12 Inc. (LRN) grew over 6.56% at $25.49 in pre-market trading today.

    Polar Power Inc. (POLA), an Electrical Equipment & Parts company, dropped about -3.35% at $3.46 in pre-market trading Thursday.

    Ayro Inc. (AYRO) stock moved up 3.77 percent to $4.4 in the pre-market trading, after the company revealed its Q3, 2020 fiscal results.

    Jaguar Health Inc. (JAGX) gained over 5.82% at $0.22 in pre-market trading Thursday 19 November 2020, following the announcement of its third-quarter 2020 financial scores.

    Sanchez Midstream Partners LP (SNMP) is down more than 0.0% at $0.5951 in pre-market hours Thursday 19 November 2020. The stock had jumped over 11.03% to $0.60 in the last trading session.

    Before the trading started on 19 November 2020, Waitr Holdings Inc. (WTRH) is up 6.46% to reach $3.38, as the company’s earnings results topped estimates. It has been trading in a 52-week range of $0.26 to $5.85.

    GreenPower Motor Company Inc. (GP) stock plunged -1.07% to $18.49 in the pre-market trading, after the report that Thermalito Union Elementary School District Agrees on purchase of six all-electric school buses from GreenPower. The most recent rating by Maxim Group, on November 02, 2020, is a Buy.

    Arcimoto Inc. (FUV) grew over 0.74% at $9.51 in pre-market trading today, after the company revealed its Q3, 2020 results, and business update.

    Kandi Technologies Group Inc. (KNDI), an Auto Manufacturers company, rose about 11.55% at $12.65 in pre-market trading Thursday, November 19, 2020, after the report that Kandi America’s EV qualified for $2,500 refund in Texas.

    China HGS Real Estate Inc. (HGSH) gained over 11.17% at $1.99 in pre-market trading Thursday 19 November 2020.

    VAALCO Energy Inc. (EGY) is down more than -9.63% at $1.22 in pre-market hours Thursday 19 November 2020, after the company revealed that it has signed a sale and purchase agreement to acquire Sasol Gabon S.A.’s 27.8% working interest in the Etame Marin block offshore Gabon. The stock had jumped over 32.35% to $1.35 in the last trading session.

    Before the trading started on 19 November 2020, Kazia Therapeutics Limited (KZIA) is down -7.87% to reach $12.41, as the announcement was made that it has executed a definitive contract with the International Coalition for Adaptive Research (GCAR) to commence Kazia’s participation in the GBM AGILE pivotal study in glioblastoma. It has been trading in a 52-week range of $2.47 to $11.10.

    Naked Brand Group Limited (NAKD) stock soared 39.0% to $0.18 in the pre-market trading.

    Phoenix Tree Holdings Limited (NYSE: DNK) shares are trading down -18.6% at $3.72 at the time of writing. The company’s 52-week range was noted as $1.27 to $13.90.