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Tag: Leap Therapeutics Inc.

  • Do You Know Why LPTX Stock Jumped 12% In Extended Trades?

    Do You Know Why LPTX Stock Jumped 12% In Extended Trades?

    On the last check Wednesday, shares of the biotechnology company focused on developing targeted and immuno-oncology therapeutics, Leap Therapeutics Inc. (LPTX) was up 12.24% at $1.65 in after-hours trading. Leap stock lost -3.29% in the regular trading to conclude the session at $1.47. LPTX shares traded between $1.445 and $1.54.

    Over the last 100 days, LPTX stock was traded for 0.42 million shares, less than its volume of 0.56 million shares traded in past session. In the last five days, LPTX shares have dropped -12.50%, while they have dropped -16.95% in the last month. LPTX stock increased on news that the company’s CEO will present a corporate overview of the company at a virtual health conference.

    Where will LPTX be presenting?

    In addition to targeted therapies, Leap Therapeutics develops products for immuno-oncology. Clinically advanced candidate DKN-01, developed by LPTX, targets the Dickkopf-1 protein (DKK1). Clinical trials involving LPTX’s DKN-01 are being conducted in esophagogastric, hepatobiliary, gynecological, and prostate cancer patients. DKN-01 will be developed by LPTX in Asia, Australia, and New Zealand in partnership with BeiGene, Ltd.

    As part of the Ladenburg Thalmann 2021 Virtual Healthcare Conference, Leap Therapeutics will be represented by Douglas E. Onsi, the company’s President and Chief Executive Officer. LPTX executive will present on Wednesday, July 14, 2021, at 1:00 pm Eastern Time. Live webcast of the presentation will be available on the Investors page of the LPTX website. For a limited time, LPTX will also offer a replay of the event on its website.

    Leap Therapeutics has developed an image analysis assay called RNAscope, which is currently being used to enroll prospective patients in clinical trials.

    • LPTX is aware of no prior RNAscope study using a digital image analysis solution for patient enrollment.
    • On May 10, Scientific Reports published LPTX’s study findings.
    • LPTX’s article was titled: “Validation of a DKK1 RNAscope chromogenic in situ hybridization assay for gastric and gastroesophageal junction adenocarcinoma tumors.”
    • Biomarker tests must be precise and robust to be used in prospective patient identification.
    • Due to the difficulty associated with manually semi-quantifying RNAscope tissue staining, LPTX and Flagship developed a novel imaging algorithm designed to identify cancer cells and quantify the DKK1 signal.

    Is LPTX benefited by this collaboration?

    Leap Therapeutics (LPTX) developed a digital algorithm that replaces manual quantification, which can be time-consuming, inaccurate, and non-reproducible. Using the digital algorithm, pathologists save time, reduce the possibility of error in manual scoring, and enable LPTX to screen patients more reliably for possible treatment benefits.

  • Leap Therapeutics Inc. (LPTX) stock surges high during pre-market trading. Let’s find out why:

    Leap Therapeutics Inc. (NASDAQ: LPTX) stock gained by 3.36% in the last trading close whereas the LPTX stock is surging by 34.96% during the pre-market trading session after Leap Therapeutics has presented the clinical data of DKN-01 on March 22, at the society of Gynecologic oncology 2021 Annual meeting on the issue of  Women’s cancer. Leap Therapeutics is dedicated to the development of targeted and immuno-oncology therapies.

    What is happening?

    At the society of Gynecologic Oncology, Leap therapeutics presented the Phase 2 clinical trial of DKN-01 as a monotherapy in addition with paclitaxel in patients with more complex gynecological malignancies. DKN-01, is the most advanced clinical candidate of LPTX which is a humanized monoclonal antibody that specifically targets the Dickkopf-1 (DKK1) protein that causes the activation of innate immune system in the tumor microenvironment. DKN-01 is currently being tested in patients with esophagogastric, hepatobiliary, gynecologic, and prostate cancers.

    Rebecca Arend, MSPH, the associate professor in University of Alabama at Birmingham O’Neal Comprehensive Cancer Center said that DKN-01 has shown promising response and also a monotherapy complete response for more than 2 years now as well as long-lasting reduction of tumor as both, a single agent and combined with paclitaxel in the study’s chronic gynecologic cancer patients. She also added that in the patients with high level of DKK1, the disease control rate and chances of survival were the highest which shows the efficiency of DKN-01 because the same group of people showed extremely unsatisfactory results towards other therapies. Upon trials it has been concluded that DKN-01 is extremely well tolerated among patients.

    Conclusion

    This positive development in Leap Therapeutics will expectedly help them to show successful results in 2021. This is definitely a great advancement in the field of pharmaceuticals that will act as a catalyst for LPTX stock price. With this growing pace, Investors will be comfortable in making long-term investments.

  • What changed for these 50 stocks in Pre-Market Session?

    What changed for these 50 stocks in Pre-Market Session?

    Oncternal Therapeutics Inc. (ONCT) stock soared 2.42% to $2.96 in the pre-market trading as the company raised the size of the formerly publicized offering and purchase on a firm commitment basis 7,258,065 shares of common stock of the Company, at a price to the public of $3.10 per share, less underwriting discounts, and commissions.

    JOYY Inc. (NASDAQ: YY) shares are trading up 19.13% at $87.75 at the time of writing as the Company revealed its Q3, 2020 Earnings. Analysts have a consensus price target of $125. The company’s 52-week range was noted as $41.33 to $108.21.

    Aptevo Therapeutics Inc. (APVO) grew over 38.17% at $48.9 in pre-market trading today after the firm offered an update on ALG.APV-527, a novel immunotherapeutic bispecific candidate aimed for the cure of multiple solid tumors expressing 5T4, a tumor-restricted antigen.

    Zomedica Pharmaceuticals Corp. (ZOM), a Drug Manufacturers – Specialty & Generic company, dropped about -2.19% at $0.1428 in pre-market trading Thursday as the firm announced its Q3 2020 results.

    Nxt-ID Inc. (NXTD) stock moved down -1.99 percent to $0.35 in the pre-market trading after the Corporation declared to adjourn the annual meeting of shareholders.

    MoneyGram International Inc. (MGI) lost over -7.9% at $6.7 in pre-market trading Thursday 19 November 2020, as the company posted 150% year-over-year cross-border deal and revenue growth for October in its direct-to-consumer digital business, MGO.

    Lexicon Pharmaceuticals Inc. (LXRX) is up more than 2.5% at $1.64 in pre-market hours Thursday 19 November 2020 following the company revealed to participate in Stifel 2020 Virtual Healthcare conference on Wednesday, November 18, 2020. The stock had dropped over -11.60% to $1.60 in the last trading session.

    Before the trading started on 19 November 2020, UP Fintech Holding Limited (TIGR) is up 4.61% to reach $5.9 after the Company announced to unveil its quarterly results on November 25, 2020. It has been trading in a 52-week range of $2.03 to $7.60.

    Asia Pacific Wire & Cable Corporation Limited (APWC) stock plunged -4.72% to $2.02 in the pre-market trading as the Corporation publicized that it will organize its 2020 Annual General Meeting on September 18, 2020, at 9:00 a.m. New York time at its headquarters located at Room B, 15th Floor, No. 77, Section 2, Dunhua South Road, Taipei, 106, Taiwan and (2) the Company has procured a US$6,000,000 secured loan from its majority shareholder, Pacific Electric Wire & Cable Co., Ltd.

    Marathon Patent Group Inc. (NASDAQ: MARA) shares are trading down -0.35% at $2.88 at the time of writing following Bitcoin self-mining company has disclosed a new investor presentation, which contains updated economic information as of November 5, 2020. The company’s 52-week range was noted as $0.35 to $5.25. Analysts have a consensus price target of $8.

    Futu Holdings Limited (FUTU) grew over 10.7% at $47.6 in pre-market trading today after the company publicized its 3rd quarter scores.

    L Brands Inc. (LB), and Apparel Retail company, rose about 16.04% at $39.0 in pre-market trading Thursday as the firm announced upbeat earnings results.

    Agora Inc. (API) stock moved up 2.45 percent to $35.99 in the pre-market trading after the Tech-giant announced its Q3 2020 results.

    ObsEva SA (OBSV) gained over 3.38% at $2.14 in pre-market trading Thursday 19 November 2020 as the biotech-firm declared the positive topline results of PROLONG, the Phase 2a proof-of-concept, randomized, double-blind, placebo-controlled trial of laropiprant in preterm labor.

    Bilibili Inc. (BILI) is up more than 4.49% at $50.0 in pre-market hours Thursday 19 November 2020, after the Corporation revealed its third-quarter 2020 results. The stock had dropped over -4.40% to $47.85 in the last trading session.

    Before the trading started on 19 November 2020, Youdao Inc. (DAO) is up 3.9% to reach $26.13, as it revealed quarterly results for the fiscal third quarter. It has been trading in a 52-week range of $13.20 to $47.70.

    Oragenics Inc. (OGEN) stock plunged -6.27% to $0.4377 in pre-market trading.

    SPI Energy Co. Ltd. (NASDAQ: SPI) shares are trading up 3.51% at $8.25 at the time of writing, as the Energy sector firm announced that its completely-owned SPI Solar, subsidiary completed the sale of a 1.015-megawatt solar project located on Hawaii’s Maui island. The company’s 52-week range was noted as $0.55 to $46.67.

    Gold Fields Limited (GFI) tumbled over -3.19% at $9.42 in pre-market trading today, following the Company revealed operational details for the 3-month period ending September 30, 2020.

    Marin Software Incorporated (MRIN), a Software – Application company, dropped about -3.38% at $2.0 in pre-market trading Thursday.

    X Financial (XYF) stock moved up 99.14 percent to $1.39 in the pre-market trading as the company disclosed that it will hold its 2020 annual general meeting of shareholders at its offices at 7/F, Block A, Aerospace Science and Technology Plaza, No.168 Haide Third Avenue, Nanshan District, Shenzhen, China on December 11, 2020, at 10:00 a.m., Beijing Time.

    Simon Property Group Inc. (SPG) lost over -2.43% at $74.75 in pre-market trading Thursday 19 November 2020 after the news that Simon has valued an upsized public offering of 19,250,000 shares of common stock at a public offering price of $72.50 per share that is expected to close November 23, 2020, subject to the satisfaction of customary closing conditions.

    ZoomInfo Technologies Inc. (ZI) is up more than 2.55% at $40.6 in pre-market hours Thursday 19 November 2020, as the Company revealed its Q3 2020 Earnings results. The stock had dropped over -2.85% to $39.59 in the last trading session.

    Before the trading started on 19 November 2020, Pan American Silver Corp. (PAAS) is down -2.98% to reach $29.98, after the Company Q3 results matched the predictions. It has been trading in a 52-week range of $10.61 to $40.11.

    Leap Therapeutics Inc. (LPTX) stock soared 6.67% to $1.6 in the pre-market trading, as the Company posted Q3 2020 Earnings results. The most recent rating by Piper Sandler, on June 29, 2020, is at an Overweight.

    Hudson Capital Inc. (NASDAQ: HUSN) shares are trading up 33.93% at $3.0 at the time of writing, following news of Hudson Capital Inc. and FreightHub, Inc. progressing further with the planned merger. The company’s 52-week range was noted as $1.60 to $9.80.

    Transocean Ltd. (RIG) grew over 4.07% at $1.28 in pre-market trading today, as the firm reported deep-water Corcovado, deep water Mykonos contract extensions.

    Acasti Pharma Inc. (ACST), a Biotechnology company, rose about 4.55% at $0.23 in pre-market trading Thursday, after the firm revealed Q2, 2021 fiscal results.

    Orbital Energy Group Inc. (OEG) stock moved up 3.56 percent to $0.8 in the pre-market trading, as the company posted Q3, 2020 earnings reports.

    Ideanomics Inc. (IDEX) gained over 10.34% at $1.28 in pre-market trading Thursday 19 November 2020 after the firm announced MEG October & Q4 sales activity.

    Virgin Galactic Holdings Inc. (SPCE) is up more than 2.04% at $23.05 in pre-market hours Thursday 19 November 2020 after the Analysts decreased its estimates by almost 25%. The stock had jumped over 5.81% to $22.59 in the last trading session.

    Before the trading started on 19 November 2020, Washington Prime Group Inc. (WPG) is down -2.15% to reach $0.742 after the report of the company to present at REITworld 2020 Virtual Investor Conference. It has been trading in a 52-week range of $0.49 to $4.49.

    Kintara Therapeutics Inc. (KTRA) stock soared 1.79% to $1.71 in the pre-market trading, after the company announced Q1, 2021 results and offered a business update.

    Electra Meccanica Vehicles Corp. (NASDAQ: SOLO) shares are trading up 7.53% at $7.43 at the time of writing. The company’s 52-week range was noted as $0.89 to $7.91.

    K12 Inc. (LRN) grew over 6.56% at $25.49 in pre-market trading today.

    Polar Power Inc. (POLA), an Electrical Equipment & Parts company, dropped about -3.35% at $3.46 in pre-market trading Thursday.

    Ayro Inc. (AYRO) stock moved up 3.77 percent to $4.4 in the pre-market trading, after the company revealed its Q3, 2020 fiscal results.

    Jaguar Health Inc. (JAGX) gained over 5.82% at $0.22 in pre-market trading Thursday 19 November 2020, following the announcement of its third-quarter 2020 financial scores.

    Sanchez Midstream Partners LP (SNMP) is down more than 0.0% at $0.5951 in pre-market hours Thursday 19 November 2020. The stock had jumped over 11.03% to $0.60 in the last trading session.

    Before the trading started on 19 November 2020, Waitr Holdings Inc. (WTRH) is up 6.46% to reach $3.38, as the company’s earnings results topped estimates. It has been trading in a 52-week range of $0.26 to $5.85.

    GreenPower Motor Company Inc. (GP) stock plunged -1.07% to $18.49 in the pre-market trading, after the report that Thermalito Union Elementary School District Agrees on purchase of six all-electric school buses from GreenPower. The most recent rating by Maxim Group, on November 02, 2020, is a Buy.

    Arcimoto Inc. (FUV) grew over 0.74% at $9.51 in pre-market trading today, after the company revealed its Q3, 2020 results, and business update.

    Kandi Technologies Group Inc. (KNDI), an Auto Manufacturers company, rose about 11.55% at $12.65 in pre-market trading Thursday, November 19, 2020, after the report that Kandi America’s EV qualified for $2,500 refund in Texas.

    China HGS Real Estate Inc. (HGSH) gained over 11.17% at $1.99 in pre-market trading Thursday 19 November 2020.

    VAALCO Energy Inc. (EGY) is down more than -9.63% at $1.22 in pre-market hours Thursday 19 November 2020, after the company revealed that it has signed a sale and purchase agreement to acquire Sasol Gabon S.A.’s 27.8% working interest in the Etame Marin block offshore Gabon. The stock had jumped over 32.35% to $1.35 in the last trading session.

    Before the trading started on 19 November 2020, Kazia Therapeutics Limited (KZIA) is down -7.87% to reach $12.41, as the announcement was made that it has executed a definitive contract with the International Coalition for Adaptive Research (GCAR) to commence Kazia’s participation in the GBM AGILE pivotal study in glioblastoma. It has been trading in a 52-week range of $2.47 to $11.10.

    Naked Brand Group Limited (NAKD) stock soared 39.0% to $0.18 in the pre-market trading.

    Phoenix Tree Holdings Limited (NYSE: DNK) shares are trading down -18.6% at $3.72 at the time of writing. The company’s 52-week range was noted as $1.27 to $13.90.