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Tag: Mereo stock

  • Positive Orbit Study Results Propel Mereo (MREO) Shares After-Hours

    Positive Orbit Study Results Propel Mereo (MREO) Shares After-Hours

    During extended trading session, Mereo BioPharma Group plc (NASDAQ: MREO) observed a favorable trend in its share prices following the announcement of fresh results from orbit studies. MREO stock rose 13.37% to $3.99 on US stock charts, following a 1.44% increase to close at $3.52 during the regular session.

    Positive Results From the Phase 2 Orbit Study

    Mereo (MREO) announced positive 14-month results from the Phase 2 section of the ongoing Phase 2/3 Orbit study, which is being conducted in collaboration with Ultragenyx Pharmaceutical. Results showed that therapy with setrusumab substantially reduced the incidence of fractures in those with osteogenesis imperfecta (OI) after at least 14 months of follow-up.

    Furthermore, by month 12, there had been significant and long-lasting gains in the lumbar spine bone mineral density (BMD) due to setrusumab therapy, with no symptoms of plateauing. The previously reported significant reduction in the annualized fracture rate for patients treated for a minimum of 6 months was maintained in those treated for at least 14 months.

    Consistent Efficacy And Safety Profile

    The results indicate that setrusumab is achieving the anticipated effects, safely decreasing fracture incidence and enhancing BMD in OI patients. The anti-sclerostin antibody remains effective even after a year, with patients continuing to show measurable gains, suggesting a prolonged response over the long term.

    The consistent and significant improvements in BMD and Z-scores across all studied OI sub-types indicate that new, stronger bone is being formed, leading to a substantial reduction in fractures across different age groups and OI types.

    Mereo BioPharma is eager to possibly provide this novel medication to more OI patients, since the Phase 3 Orbit and Cosmic investigations are now completely recruited. As of the data cut-off date, no treatment-related serious adverse events were observed.

    The reported adverse events were in line with those seen in the Asteroid study, with infusion-related reactions and headaches being the most common. No hypersensitivity reactions to setrusumab were observed.

    Mereo BioPharma’s ongoing commitment to improving outcomes for OI patients is reflected in these promising results, paving the way for further advancements in treatment options.

  • ‎26 stocks making the biggest moves premarket today

    ‎26 stocks making the biggest moves premarket today

    ‎Mereo BioPharma Group plc (MREO) stock plunged -7.78% to $3.32 in the pre-‎market trading after declaring collaboration and license agreement with Ultragenyx Pharmaceutical ‎Inc. (RARE), for Setrusumab in Osteogenesis Imperfecta.‎

    ‎Naked Brand Group Limited (NASDAQ: NAKD) shares are trading up ‎‎11.45% ‎at ‎‎$0.2044 at the time of writing. Company’s 52-week ranged between $0.07 to $3.70.‎

    ‎Exela Technologies Inc. (XELA) is down more than -9.79% at $0.4128 in pre-market ‎hours Monday December 21, 2020 following the announcement from the firm that it has entered into ‎a 5-year, $145 million term loan facility with Angelo Gordon, a global alternative investment firm. The ‎stock had jumped over 26.10% to $0.46 in the last trading session.‎

    ‎Zomedica Corp. (ZOM) tumbled over -5.22% at $0.1959 in pre-market trading today.‎

    Before the trading started on December 21, 2020, BlackBerry Limited (BB) is down -‎‎3.17% to reach $6.73 after releasing financial results for the three months ended November 30, 2020. It ‎has been trading in a 52-week range of $2.70 to $9.69.‎

    ‎General Electric Company (GE), a Specialty Industrial Machinery company, dropped ‎about -6.11% at $10.15 in pre-market trading Monday after announcing expiration and results of its ‎debt tender offers.‎

    ‎Phunware Inc. (PHUN) lost over -10.38% at $0.95 in pre-‎‎market ‎trading ‎Monday ‎December 21, 2020.‎

    ‎American Airlines Group Inc. (AAL) lost over -7.03% at $15.35 in pre-market trading ‎Monday December 21, 2020.‎

    Before the trading started on December 21, 2020, Carnival Corporation & Plc (CCL) is ‎down -9.79% to reach $19.36. It has been trading in a 52-week range of $7.80 to $51.94.‎

    ‎FuelCell Energy Inc. (FCEL) stock moved down -4.3 percent to $8.9 in the pre-‎market trading after declaring that state regulators have improperly rescinded RFP awards for three ‎fuel cell projects previously selected in the Shared Clean Energy Facility program, putting its state high ‎tech manufacturing job growth at risk.‎

    ‎Exicure Inc. (XCUR) stock soared 7.04% to $2.13 in the pre-‎‎market ‎trading. ‎The ‎most ‎recent rating by BMO Capital Markets, on December 18, 2020, is ‎an ‎Outperform.‎

    ‎Genius Brands International Inc. (GNUS), a Entertainment company, rose about ‎‎3.18% at $1.62 in pre-market trading Monday. The firm recently revealed that it has licensed streaming ‎and select video-on-demand rights to the hit family series, The Wubbulous World of Dr. Seuss (20 x ‎‎22’), from The Jim Henson Company on Kartoon Channel!‎

    ‎SolarWinds Corporation (NYSE: SWI) shares are trading ‎up ‎‎6.7% ‎at ‎‎$15.13 ‎at ‎the ‎time of writing. Company’s 52-week ranged between $11.50 ‎to ‎‎$24.34. ‎Analysts ‎have ‎a ‎consensus ‎price target of $26. ‎

    ‎Norwegian Cruise Line Holdings Ltd. (NCLH) lost over -10.01% at $22.66 in pre-‎market trading Monday December 21, 2020 after reporting that it has closed its previously announced ‎private offering of $850 million aggregate principal amount of its 5.875% senior notes due 2026 (the ‎‎“Notes”).‎

    Before the trading started on December 21, 2020, Nokia Corporation (NOK) is down ‎‎-5.25% to reach $3.79. The company recently declared that it has launched 5G services with Polkomtel, ‎operator of the Plus network, in the capital city of Warsaw as well as other major cities in the eastern ‎part of the country. It has been trading in a 52-week range of $2.34 to $5.14.‎

    ‎Corbus Pharmaceuticals Holdings Inc. (CRBP) is up more than 12.0% at $1.68 in pre-‎‎‎‎‎‎‎‎market hours Monday December 21, 2020. The stock had jumped ‎over ‎‎11.11% ‎to ‎‎$1.50 ‎in ‎the ‎last ‎trading session.‎

    ‎Schlumberger Limited (NYSE: SLB) shares are trading down -6.95% at $20.76 at the ‎time of writing. The firm will hold a conference call on January 22, 2021 to discuss the results for the ‎fourth quarter and full year ending December 31, 2020. Company’s 52-week ranged between $11.87 to ‎‎$41.14.‎

    ‎Exxon Mobil Corporation (NYSE: XOM) shares are trading down -5.27% ‎at ‎‎$40.48 ‎at ‎the time of writing. Company’s 52-week ranged between $30.11 to $71.37. Analysts ‎have ‎a ‎consensus ‎price target of $52.‎

    ‎Transocean Ltd. (RIG) is down more than -14.92% at $2.11 in pre-market hours ‎Monday December 21, 2020 after announcing successful court ruling granting its motion for summary ‎judgment and holding internal reorganization did not violate indenture. The stock had dropped over -‎‎3.50% to $2.48 in the last trading session.‎

    ‎Simon Property Group Inc. (SPG) tumbled over -5.07% at $81.1 in pre-market ‎trading today. The firm recently declared a common stock dividend for the fourth quarter 2020.‎
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    ‎Energy Transfer LP (ET), a Oil & Gas Midstream company, dropped about -‎‎‎‎5.9% ‎at ‎‎$6.38 in pre-market trading Monday.‎

    ‎Cinedigm Corp. (CIDM) stock moved up 4.11 percent to $0.798 in the pre-market ‎trading after revealing the launch of The Bob Ross Channel on the Roku platform.‎

    Before the trading started on December 21, 2020, Coty Inc. (COTY) is down -6.15% ‎to reach $6.56. The company lately reported two additions to its Board of Directors with the ‎appointments of Anna Adeola Makanju and Mariasun Aramburuzabala Larregui. It has been trading in ‎a 52-week range of $2.65 to $13.01.‎

    ‎JPMorgan Chase & Co. (JPM) gained over 2.24% at $121.75 in pre-‎‎‎‎market ‎trading ‎Monday December 21, 2020. ‎

    ‎Apache Corporation (NASDAQ: APA) shares are trading down -11.29% at $13.6 at ‎the time of writing after announcing the donation of more than 64,000 trees to 56 nonprofit partner ‎organizations through the annual Apache Tree Grant Program. Company’s 52-week ranged between ‎‎$3.80 to $33.77. Analysts have a consensus price target of $16.‎

  • Pre-Market Cues: 28 Stocks Roaring for Change On December 18th

    Pre-Market Cues: 28 Stocks Roaring for Change On December 18th

    Seneca Biopharma Inc. (SNCA), a Biotechnology company, rose about 0.2% at $0.96 in pre-market trading Friday after declaring merger agreement with Leading BioSciences, Inc. under which a wholly owned subsidiary of Seneca will merge with LBS in an all-stock transaction.

    Palantir Technologies Inc. (PLTR) lost over -3.97% at $26.15 in pre-market trading Friday December 18, 2020 after reporting that it will hold its inaugural “Live Demo Day” on Tuesday, January 26, 2021 at 4:30pm ET.

    Atossa Therapeutics Inc. (ATOS) stock plunged -0.02% to $0.86 in the pre-market trading following its declaration of pricing of $14.0 million registered direct offering priced at-the-market. The most recent rating by Maxim Group, on January 26, 2018, is a Buy.

    Virgin Galactic Holdings Inc. (NYSE: SPCE) shares are trading down -6.27% at $23.9 at the time of writing. The company recently revealed an update following its test flight on December 12, 2020. Company’s 52-week ranged between $9.06 to $42.49. Analysts have a consensus price target of $19.

    BlackBerry Limited (BB), a Software – Infrastructure company, dropped about -4.36% at $7.9 in pre-market trading Friday after releasing its financial results for the three months ended November 30, 2020

    Before the trading started on December 18, 2020, Uxin Limited (UXIN) is up 4.5% to reach $1.16 following its announcement of unaudited financial results for the quarter ended September 30, 2020. It has been trading in a 52-week range of $0.72 to $3.07.

    Coeur Mining Inc. (CDE) stock plunged -2.98% to $10.76 in the pre-market trading. The firm recently revealed details of the expansion of its Rochester silver-gold mine in Nevada, reflecting significant reserve growth and the benefits of a larger-scale expansion project. The most recent rating by Noble Capital Markets, on September 14, 2020, is an Outperform.

    Novan Inc. (NASDAQ: NOVN) shares are trading up 6.25% at $0.68 at the time of writing. The company lately reported that it has enrolled 525 patients of the approximately 850 patients expected to enroll in the B-SIMPLE4 pivotal Phase 3 clinical study of SB206. Company’s 52-week ranged between $0.22 to $3.72.

    CNS Pharmaceuticals Inc. (CNSP), a Biotechnology company, rose about 15.2% at $2.88 in pre-market trading Friday after announcing FDA approval of IND application for its brain cancer drug candidate Berubicin.

    United States Steel Corporation (X) stock moved down -4.26 percent to $17.77 in the pre-market trading after reporting that fourth quarter 2020 adjusted EBITDA is expected to be approximately $55 million and expected fourth quarter 2020 adjusted diluted loss per share to be approximately ($0.85).

    BioCardia Inc. (BCDA) lost over -6.09% at $4.01 in pre-market trading Friday December 18, 2020 following an announcement from the firm that the independent Data Safety Monitoring Board (DSMB) has completed its prespecified data review for the Phase III pivotal CardiAMP Heart Failure Trial.

    Before the trading started on December 18, 2020, Ampio Pharmaceuticals Inc. (AMPE) is up 8.43% to reach $1.93 after revealing the completion of its Phase I clinical trial and initiation of the first steps for a global Phase II clinical trial for intravenous (“IV”) Ampion treatment in COVID-19 patients. It has been trading in a 52-week range of $0.31 to $1.69.

    Drive Shack Inc. (NYSE: DS) shares are trading up 5.47% at $3.47 at the time of writing following the opening of its 65,000-square-foot entertainment golf venue located in Orlando. Company’s 52-week ranged between $0.86 to $4.19. Analysts have a consensus price target of $4.

    IZEA Worldwide Inc. (IZEA) tumbled over -3.7% at $1.04 in pre-market trading today. The company recently reported that it has just been awarded a mid-six figure contract from a Fortune 500 Manufacturer.

    Exela Technologies Inc. (XELA), a Software – Application company, rose about 81.87% at $0.66 in pre-market trading Friday after declaring that it has entered into a 5-year, $145 million term loan facility with Angelo Gordon, a global alternative investment firm.

    FedEx Corporation (FDX) stock moved down -2.89 percent to $283.8 in the pre-market trading after declaring strong results for the quarter ended November 30.

    Guardion Health Sciences Inc. (GHSI) stock plunged -2.13% to $0.23 in the pre-market trading. The firm recently declared progress on the introduction of its new vision support/energy drink, Epiq-V, which is under development for the United States and international markets.

    Amyris Inc. (NASDAQ: AMRS) shares are trading up 3.68% at $4.23 at the time of writing. Company’s 52-week ranged between $1.40 to $6.07. Analysts have a consensus price target of $3.35.

    Mereo BioPharma Group plc (MREO), a Biotechnology company, rose about 40.27% at $3.1 in pre-market trading Friday following the declaration of a license and collaboration agreement with Ultragenyx Pharmaceutical Inc. (RARE), for setrusumab, a monoclonal antibody in clinical development for osteogenesis imperfecta (OI).

    Surface Oncology Inc. (SURF) gained over 17.51% at $10.0 in pre-market trading Friday December 18, 2020 after revealing exclusive license agreement with GSK for novel immunotherapy program.

    Neovasc Inc. (NVCN) is down more than -8.52% at $0.91 in pre-market hours Friday December 18, 2020 after reporting the publication of peer-reviewed article in EuroIntervention. The stock had jumped over 3.61% to $0.99 in the last trading session.

    BioLineRx Ltd. (BLRX) tumbled over -1.1% at $2.7 in pre-market trading today. The firm lately declared final results from Phase 2a COMBAT/KEYNOTE-202 triple combination study of Motixafortide in second line Metastatic Pancreatic Cancer (PDAC).

    VYNE Therapeutics Inc. (VYNE), a Biotechnology company, rose about 8.05% at $1.88 in pre-market trading Friday after declaring the successful completion of its End-of-Phase 2 Meeting with the U.S. Food and Drug Administration (FDA).

    Before the trading started on December 18, 2020, Mesoblast Limited (MESO) is down -26.75% to reach $9.94 after announcing an update on COVID-19 ARDS trial. It has been trading in a 52-week range of $3.12 to $21.28.

    Applied DNA Sciences Inc. (APDN) stock plunged -12.02% to $5.49 in the pre-market trading after reporting consolidated financial results for the full fiscal year and quarter ended September 30, 2020. The most recent rating by H.C. Wainwright, on July 20, 2020, is a Buy.

    Conformis Inc. (NASDAQ: CFMS) shares are trading up 3.8% at $0.6693 at the time of writing. The firm lately revealed the U.S. commercial launch of the Company’s new Cordera™ Match Hip System. Company’s 52-week ranged between $0.50 to $1.66.

    Auris Medical Holding Ltd. (EARS) grew over 1.5% at $2.7 in pre-market trading today. The company recently provided a business update related to the Company’s funding position, its AM-301 program for the protection against airborne pathogens and allergens and the ongoing strategy review process.

    Sonoma Pharmaceuticals Inc. (SNOA) stock moved up 19.79 percent to $9.14 in the pre-market trading following the announcement of partnership with Gabriel Science, LLC for dental.