Tag: Opiant

  • Is This Why The Opiant (OPNT) Stock Rose In Extended Session?

    Is This Why The Opiant (OPNT) Stock Rose In Extended Session?

    Shares of the specialty pharmaceutical company developing medicines to treat addictions and drug overdose, Opiant Pharmaceuticals Inc. (OPNT) gained 5.20% to $18.00 in Tuesday’s after-hours trading. In the morning session, Opiant stock gained 4.27% to finish at $17.11. There were 58042 shares traded for OPNT stock, a volume which was below the average daily trading volume of 0.17 million shares published for the last 50 days.

    Over the last five days, OPNT stock has declined 3.63%; however, over the last month, it has gained 23.09%. This year, the price of OPNT stock has risen 81.63 percent and has surged by 62.18% over the last three months. As a result of the news of its grant of inducement awards to new employees, OPNT stock surged.

    How did OPNT grant the award?

    Pharmaceutical company Opiant Pharmaceuticals develops medicine to treat drug overdoses and addictions. As a treatment for opioid overdoses, OPNT provides NARCAN nasal spray, an opioid-reversing treatment. Products that are in OPNT’s pipeline include treatments for opioid overdose reversal, alcohol use disorders, acute cannabinoid overdoses, and opioid use disorders. The company used to be known as Lightlake Therapeutics Inc. and since January 2016 has changed its name to Opiant Pharmaceuticals, Inc.

    Opiant Pharmaceuticals announced yesterday it had granted incentive awards to two new employees, an announcement made by OPNT in compliance of Nasdaq Market rules.

    • In an action approved by its Compensation Committee, OPNT Board of Directors granted a non-qualified stock option.
    • A grant of restricted stock units covering 15,000 shares of common stock along with an option to purchase 50,000 shares of OPNT common stock.
    • OPNT granted it as an inducement incentive to Matthew Ruth, its new Chief Commercial Officer, for his acceptance of employment with the Company in accordance with Nasdaq listing rules.
    • A further 6,500 shares of OPNT common stock and restricted stock units were approved by the Committee as additional non-qualified stock options.
    • A total of 3,200 shares of OPNT common stock will be delivered as a material incentive to another new employee joining the organization.

    Terms under which OPNT will execute the options:

    The exercise price for OPNT options is $16.41, which is the closing price of Opiant’s common stock on the Nasdaq Stock Market on July 19, 2021, the grant date. A restricted stock unit award will vest over a four-year period, with 25% vesting on the one-year anniversary of the grant date and the subsequent 25% vesting each subsequent anniversary of the grant date, provided an employee remains employed by Opiant (OPNT) through these vesting dates. OPNT’s existing Inducement Plan, as well as the stock option contract among employees and restricted stock unit contracts between employees, governs the exercise of stock options and the award of restricted stock units.

  • Opiant Pharmaceuticals, Inc. (OPNT) Stock Surges Following Positive Topline Data from OPNT003 Study

    Opiant Pharmaceuticals, Inc. (OPNT) Stock Surges Following Positive Topline Data from OPNT003 Study

    Opiant Pharmaceuticals, Inc. (OPNT) stock prices were up a significant 32.54% shortly after market trading commenced on July 7th, 2021, bringing the price per share up to USD$17.57

    OPNT003

    July 7th, 2021 saw the company announce top-line results from its confirmatory pharmacokinetic study for the nasal nalmefene, OPNT003, for use in cases of opioid overdose. The study had a total enrollment of 68 subjects and was designed to compare 3mg nelmafene nasal spray with 1mg intramuscular nalmafene injection. As per an initial analysis, nasal nalmefene reported significantly higher plasma concentrations as compared to the intramuscular injections. A previously completed pilot study pegged the time for nasal nalmefene to achieve maximum plasma concentrations at 15 minutes, with the finding being consolidated in the OPNT003 study.

    Competitive Edge

    Currently, the only treatment for opioid overdose that has been approved by the FDA is Naloxone, which has a half life of roughly 2 hours. April saw the company initiate a pharmacodynamic study in healthy subjects, which was designed to compare OPNT003 with nasal naloxone in reversing the respiratory depression produced by the synthetic opioid remifentanil.

    Pushing for Commercialization

    Topline data from the study is expected in the fourth quarter of 2021. Accordingly, OPNT is expecting to submit a marketing application to the U.S Food and Drug Administration by the first quarter of 2022 at the latest. OPNT003 development has been facilitated by grants from the National Institute on Drug Abuse and the Biological Advance Research and Development Agency.

    Scope of OPNT003

    Opioid overdoses have reached unprecedented levels of being the cause of deaths, with the Centers for Disease Control and Prevention reporting more than 69,000 opioid overdose deaths in the 12 months through November 2020. 80% of these are linked to potent illicit synthetic opioids, especially fentanyl. 2017 saw the NIH leadership call for opioid reversal agents that were longer lasting and stronger, as a response to the potency of synthetic opioids in the interest of controlling the proliferation of the public health crisis.

    Future Outlook for OPNT

    Armed with the successful results of its OPNT003 study, OPNT is poised to push for the commercialization and proliferation of its flagship treatment. The company is keen to establish an expansive market footprint, while addressing a rising cause of concern for public health.